Historical DNA Analysis for Native American Ancestry Verification

A complex genealogical investigation required DNA evidence to verify a potential father-son relationship between a Scottish historical figure and a Cherokee tribal member, where traditional documentation was lost during the Civil War era. This investigation was particularly significant given the importance of family history in Native American cultures and the historical challenges in maintaining documented lineages.

• Analyse Y-chromosome DNA profiles across family lines

• Evaluate historical documentation for contextual support

• Quantify relationship likelihood through STR analysis

• Compare genetic variation patterns between families

• Provide conclusive evidence of paternal relationships

1. DNA Profile Analysis

• Collected Y-chromosome DNA samples

• Examined 30 Y-STR markers

• Identified genetic variations

• Mapped generational distances

2. Historical Documentation Review

• Assessed available civil records

• Evaluated tribal documentation

• Analysed contextual evidence

• Integrated historical timelines

3. Statistical Analysis

• Calculated STR variation rates

• Determined generational distance

• Assessed relationship probabilities

• Validated findings across samples

Quantitative Outcomes

• Eight Y-STR differences identified across 30 markers

• ~370-year generational distance established

• 10-20 generation separation confirmed

• Seven individuals' paternal lineages verified

Clinical Benefits

• Confirmed historical family connections

• Strengthened tribal historical record

• Enhanced genealogical documentation

• Preserved cultural heritage information

"Through precise genetic analysis and careful consideration of historical context, we were able to bridge a gap in Native American family history that traditional documentation could not fill. This work demonstrates the power of combining modern DNA technology with cultural heritage preservation."

Michael Brown Lead Genetic Genealogist

• Sample Collection: 2 months

• DNA Analysis: 3 months

• Historical Research: 2 months

• Final Analysis and Report: 1 month

Expanding the methodology to address similar genealogical questions in other Native American families and developing more comprehensive approaches to combining genetic evidence with historical documentation for ancestry verification.